ZIKV (strain Zika SPH2015) Membrane Protein, Fc Tag
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产品编号
KMP4918
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别名
寨卡病毒膜蛋白, ZIKV Membrane, M Protein, ZIKV Membrane Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 寨卡病毒膜蛋白, ZIKV Membrane, M Protein, ZIKV Membrane Protein |
Catalog Number | KMP4918 |
Product Description | The ZIKV (strain Zika SPH2015) Membrane Protein(KMP4918) is produced in HEK293 Cells. A DNA sequence encoding the Zika virus (strain Zika SPH2015) M / Membrane (ALU33341.1) (Ala216-Ser290) was expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | ZIKV Membrane |
Species | ZIKV |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >80% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 20mM Tris, 500mM NaCl, 20% Glycerol, pH8.0 |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
膜蛋白(prM)是包膜蛋白的前体,协助其正确折叠,并在病毒成熟过程中被切割为成熟形式(M蛋白)。
不影响,Fc标签增强蛋白稳定性,并可通过Fc受体增强抗原提呈,提高疫苗免疫效果。
是的,prM蛋白与登革病毒等黄病毒存在交叉表位,可用于广谱抗体筛选。
通过SDS-PAGE分析切割前后的分子量变化(prM≈26 kDa → M≈8 kDa + pr≈18 kDa)。
是的,已用于小鼠模型,推荐与佐剂(如Alhydrogel)联用以增强免疫应答。