ZIKV (strain Zika SPH2015) Envelope Protein, Fc Tag
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产品编号
KMP4917
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别名
寨卡病毒包膜蛋白, ZIKV Envelope, E Protein, ZIKV Envelope Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 寨卡病毒包膜蛋白, ZIKV Envelope, E Protein, ZIKV Envelope Protein |
Catalog Number | KMP4917 |
Product Description | The ZIKV (strain Zika SPH2015) Envelope Protein(KMP4917) is produced in HEK293 Cells. A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (domain III) (ALU33341.1) (Val593-Lys699) was expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | ZIKV Envelope |
Species | ZIKV |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
包膜蛋白介导病毒与宿主细胞(如神经细胞)的黏附和膜融合,是中和抗体的主要靶标,也是疫苗研发的核心抗原。
Fc标签(人IgG Fc段)延长蛋白半衰期,支持Protein A/G亲和纯化,并可用于抗体依赖性细胞功能(ADCC)研究。
是的,包膜蛋白可设计为亚单位疫苗或mRNA疫苗抗原,诱导中和抗体以阻断病毒入侵。
通过圆二色光谱(CD)分析二级结构(β-折叠为主),或假病毒中和实验验证功能性构象。
-80℃保存,溶解后分装使用;避免反复冻融,缓冲液中含0.01% Tween-20防止聚集。