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VZV (strain Oka vaccine) GP B Protein

VZV (strain Oka vaccine) GP B Protein

产品编号

KMP4913

别名

水痘带状疱疹病毒包膜糖蛋白B, VZV GP B, Glycoprotein B, VZV GP B Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias水痘带状疱疹病毒包膜糖蛋白B, VZV GP B, Glycoprotein B, VZV GP B Protein
Catalog NumberKMP4913
Product DescriptionThe VZV (strain Oka vaccine) GP B Protein(KMP4913) is produced in CHO Cells. A DNA sequence encoding the Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B (Q4JR05) was expressed with a polyhistidine tag at the C-terminus.
Molecular NameVZV GP B
SpeciesVZV
HostCHO Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
FAQ
  • Q1-GP B蛋白的疫苗学意义是什么?

    作为Oka减毒疫苗株的核心抗原,GP B可诱导细胞免疫应答,预防水痘和带状疱疹。

  • Q2-该蛋白是否形成功能性复合物?

    GP B需与GP H/L形成异源三聚体(gB/gH/gL)才能介导膜融合,单独表达仅用于表位研究。

  • Q3-能否用于诊断试剂开发?

    是的,作为ELISA包被抗原检测患者血清中的VZV特异性IgG/IgM抗体。

  • Q4-如何验证蛋白的天然构象?

    通过圆二色光谱(CD)分析其α-螺旋和β-折叠比例,或电镜观察多聚体形态。

  • Q5-储存条件有何要求?

    溶于PBS(pH 7.4)含5%海藻糖,-80℃保存,避免多次冻融导致聚集。

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