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VZV GP E Protein(ECD), His Tag

VZV GP E Protein(ECD), His Tag

产品编号

KMP4912

别名

水痘带状疱疹病毒包膜糖蛋白E, VZV GP E, Glycoprotein E, VZV GP E Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias水痘带状疱疹病毒包膜糖蛋白E, VZV GP E, Glycoprotein E, VZV GP E Protein
Catalog NumberKMP4912
Product DescriptionThe VZV GP E Protein(KMP4912) is produced in HEK293 Cells. A DNA sequence encoding the Varicella-zoster virus (VZV) / HHV-3 gE / glycoprotein E (Q9J3M8) (Met1-Tyr538) was expressed with a polyhistidine tag at the C-terminus.
Molecular NameVZV GP E
SpeciesVZV
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
FAQ
  • Q1-GP E蛋白在VZV感染中的功能是什么?

    GP E是水痘-带状疱疹病毒的包膜糖蛋白,参与病毒与宿主细胞(如上皮细胞和神经元)的黏附和膜融合。

  • Q2-ECD(胞外域)的优势是什么?

    去除跨膜区提高可溶性,保留受体结合能力,适用于抗体中和研究或ELISA检测抗原开发。

  • Q3-能否用于疫苗研发?

    GP E是亚单位疫苗候选抗原,可诱导中和抗体,但需与佐剂联用增强免疫原性。

  • Q4-如何避免蛋白降解?

    添加1 mM EDTA和蛋白酶抑制剂,分装后-80℃保存,避免反复冻融。

  • Q5-是否支持动物模型免疫实验?

    是的,已用于豚鼠模型评估免疫保护效果,推荐使用弗氏佐剂。

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