RVFV (strain MP12) GP Protein, His Tag
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产品编号
KMP4892
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别名
裂谷热病毒包膜糖蛋白, RVFV GP, Glycoprotein, RVFV GP Protein
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规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 裂谷热病毒包膜糖蛋白, RVFV GP, Glycoprotein, RVFV GP Protein |
| Catalog Number | KMP4892 |
| Product Description | The RVFV (strain MP12) GP Protein(KMP4892) is produced in Insect Cells. A DNA sequence encoding the Rift Valley fever virus (RVFV) (strain MP12) Gc (ABD38821.1) (Cys691-Ser1139) was expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | RVFV GP |
| Species | RVFV |
| Host | Insect Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 20mM Tris, 150mM NaCl, pH8.5 |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
FAQ
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Q1-GP蛋白的功能是什么？
GP介导病毒与宿主细胞（如肝细胞）结合，并通过膜融合促进病毒入侵，是疫苗和药物靶点。
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Q2-MP12株的安全性如何？
MP12是减毒活疫苗株，其GP蛋白可用于研究免疫保护机制，操作需在BSL-2实验室进行。
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Q3-如何验证GP的膜融合活性？
通过脂质体融合实验或细胞-细胞融合实验（如表达GP的效应细胞与靶细胞共培养）。
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Q4-是否支持动物免疫实验？
是的，已用于小鼠和绵羊模型，诱导中和抗体并评估抗病毒效果。
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Q5-蛋白的糖基化修饰是否保留？
哺乳动物细胞（如HEK293）表达保留N-糖基化，昆虫细胞表达可能简化糖链结构。
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