RSV (A2) PreF Protein
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产品编号
KMP4890
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别名
人呼吸道合胞病毒前融合蛋白, RSV PreF, Prefusion Glycoprotein F Protein, RSV PreF Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 人呼吸道合胞病毒前融合蛋白, RSV PreF, Prefusion Glycoprotein F Protein, RSV PreF Protein |
Catalog Number | KMP4890 |
Product Description | The RSV (A2) PreF Protein(KMP4890) is produced in CHO Cells. |
Molecular Name | RSV PreF |
Species | RSV |
Host | CHO Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
PreF(融合前构象)是中和抗体的主要靶点,比PostF更稳定且免疫原性更强,是疫苗设计的理想抗原。
通过引入稳定突变(如DS-Cav1)和低温保存(-80℃),避免向融合后构象(PostF)转化。
是的,免疫动物后可筛选针对抗原位点Ø的高效中和抗体(如帕利珠单抗类似物)。
可提供X射线晶体学或冷冻电镜结构数据(需合作研究)。
干冰运输,到货后立即-80℃保存,避免温度波动导致构象变化。