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雌二醇小鼠单抗

雌二醇小鼠单抗

产品编号

PA109

别名

雌二醇, 雌二醇单抗, Estradiol

规格
  • 100μl
  • 200μl
产品介绍
Alias雌二醇, 雌二醇单抗, Estradiol
Catalog NumberPA109
Molecular NameEstradiol
Size100μl,200μl
ClonityMonoclonal Antibody
Concentration1mg/ml
PurificationProtein A/G
Formulation0.01M PBS (pH 7.4) containning 10% glycerol.
BackgroundEstradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a feminine pattern of fat distribution in women and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus, and vagina during puberty, adulthood, and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in men are much lower compared to those in women, estradiol has important roles in men as well. Aside from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species.Estradiol is produced especially within the follicles of the ovaries, but also in other tissues including the testicles, the adrenal glands, fat, liver, the breasts, and the brain. Estradiol is produced in the body from cholesterol through a series of reactions and intermediates. The major pathway involves the formation of androstenedione, which is then converted by aromatase into estrone and is subsequently converted into estradiol. Alternatively, androstenedione can be converted into testosterone, which can then be converted into estradiol. Upon menopause in women, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels.
ImmunogenBSA conjugated estradiol
ApplicationELISA, POCT
Storage ConditionStore at -20 ℃ for 3 months, -70 ℃ for 12 months
Cross-reactivityThis antibody is specific for estradiol antigen and does not react with other molecules.

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