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Human IL18 Protein

Human IL18 Protein

产品编号

KMPH1232

别名

白介素-18, IL18, interleukin 18, IGIF, IL-18, IL-1g, IL1F4

规格
  • 10ug
  • 100ug
  • 500ug
  • 1mg
产品介绍
Alias白介素-18, IL18, interleukin 18, IGIF, IL-18, IL-1g, IL1F4
Catalog NumberKMPH1232
Molecular NameInterleukin 18 IL 18
SpeciesHuman
HostE.coli
Size10ug, 100ug, 500ug, 1mg
Purity> 95% as determined by Tris-Bis PAGE, > 95% as determined by HPLC
EndotoxinLess than 1EU per ug by the LAL method.
FormulationLyophilized from 0.22um filtered solution in 20mM PB, 250mM NaCl, 50mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
BackgroundInterleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
ApplicationSDS-PAGE, WB, ELISA
TagNo Tag
Biological ActivityImmobilized Human IL-18 at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-18BP, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
Predicted N TerminusTyr 37
ReconstitutionCentrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
SequenceYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISM YKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFF QRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTV QNED
Molecular WeightThe protein has a predicted MW of 18.2 kDa same as Tris-Bis PAGE result.
Uniprot IDQ14116-1
Note仅供科研使用

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