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Recombinant Human FGF Acidic/FGF1 Protein, No Tag

Recombinant Human FGF Acidic/FGF1 Protein, No Tag

产品编号

KMH1083

别名

酸性成纤维细胞生长因子, AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF 1, HBGF1, HBGF 1, GLIO703, ECGF beta, FGF alpha, fibroblast growth factor 1

规格
  • 50ug
  • 500ug
  • 1mg
产品介绍
Alias酸性成纤维细胞生长因子, AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF 1, HBGF1, HBGF 1, GLIO703, ECGF beta, FGF alpha, fibroblast growth factor 1
Catalog NumberKMH1083
Molecular NameFGF1
SpeciesHuman
HostE.coli
Size50ug, 500ug, 1mg
Purity>95% as determined by reducing SDS-PAGE
EndotoxinLess than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
BackgroundFGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
ApplicationSDS-PAGE, WB, ELISA
TagNo Tag
ReconstitutionCentrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
SequenceAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDR SDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLER LEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
Molecular Weight17.3 KDa
Uniprot IDP05230
Note仅供科研使用

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