MA2608
Influenza A H3N2, anti Influenza A H3N2 Neuraminidase/NA antibody, anti-Neuraminidase/NA antibody, Rabbit anti Influenza A H3N2 Neuraminidase/NA polyclonal antibody, anti Influenza A H3N2 Neuraminidase/NA pAb
| Alias | Influenza A H3N2, anti Influenza A H3N2 Neuraminidase/NA antibody, anti-Neuraminidase/NA antibody, Rabbit anti Influenza A H3N2 Neuraminidase/NA polyclonal antibody, anti Influenza A H3N2 Neuraminidase/NA pAb |
| Catalog Number | MA2608 |
| Product Description | The Rabbit anti Influenza A H3N2 Neuraminidase polyclonal Antibody is produced in rabbits immunized with purified, recombinant Influenza A H3N2 (A/Babol/36/2005) Neuraminidase / NA (His36-Pro459). Total IgG was purified by Protein A affinity chromatography. |
| Host | Rabbit |
| Size | 20ul, 100ul |
| Clonity | Polyclonal |
| Purification | Protein A/G |
| Formulation | 0.2 μm filtered solution in PBS |
| Background | Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell. Influenza neuraminidase is composed of four identical subunits arranged in a square. It is normally attached to the virus surface through a long protein stalk. The active sites are in a deep depression on the upper surface. They bind to polysaccharide chains and clip off the sugars at the end. The surface of neuraminidase is decorated with several polysaccharide chains that are similar to the polysaccharide chains that decorate our cell surface proteins. Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of the influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme that facilitates virus release and efficient spread of the progeny virus from cell to cell. Influenza antibody and influenza antibodies are very important research tools for influenza diagnosis, influenza vaccine development, and anti-influenza virus therapy development. The monoclonal or polyclonal antibody can be raised with protein based antigen or peptide-based antigen. Antibodies raised with protein-based antigen could have better specificity and/or binding affinity than antibodies raised with peptide based antigen, but the cost associated with the recombinant protein antigen is usually higher. Anti-influenza virus hemagglutinin (HA) monoclonal antibody or polyclonal antibody can be used for ELISA assay, western blotting detection, Immunohistochemistry (IHC), flow cytometry, neutralization assay, hemagglutinin inhibition assay, and early diagnosis of influenza viral infection. Sino Biological has developed state-of-the-art monoclonal antibody development technology platforms: mouse monoclonal antibody and rabbit monoclonal antibody. Our rabbit monoclonal antibody platform is one of a kind and offers some unique advantages over mouse monoclonal antibodies, such as high affinity, low cross-reactivity with rabbit polyclonal antibodies. |
| Immunogen | Recombinant Influenza A H3N2 (A/Babol/36/2005) Neuraminidase / NA ( His36-Pro459). |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Shipping Condition | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Cross-reactivity | Influenza A H3N2 (A/Babol/36/2005) Neuraminidase / NA |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
是的，已验证用于WB、ELISA及免疫沉淀（IP），需变性条件暴露神经氨酸酶（NA）表位。
多克隆抗体识别多个表位，灵敏度高但可能交叉反应；单克隆抗体特异性强但仅针对单一表位。
需验证体内兼容性，建议预实验评估非特异性结合及毒性。
可能与其他亚型（如H1N1）有交叉反应，建议使用重组蛋白验证特异性。
标准浓度为1 mg/ml，具体使用浓度需根据实验优化。
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