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Mouse anti Influenza A H3N2 Hemagglutinin monoclonal Antibody

Mouse anti Influenza A H3N2 Hemagglutinin monoclonal Antibody

产品编号

MA2607

别名

Influenza A H3N2, anti Influenza A H3N2 Hemagglutinin/HA antibody, anti-Hemagglutinin/HA antibody, Mouse anti Influenza A H3N2 Hemagglutinin/HA monoclonal antibody, anti Influenza A H3N2 Hemagglutinin/HA mAb

规格
  • 20ul
  • 100ul
产品介绍
AliasInfluenza A H3N2, anti Influenza A H3N2 Hemagglutinin/HA antibody, anti-Hemagglutinin/HA antibody, Mouse anti Influenza A H3N2 Hemagglutinin/HA monoclonal antibody, anti Influenza A H3N2 Hemagglutinin/HA mAb
Catalog NumberMA2607
Product DescriptionThe Mouse anti Influenza A H3N2 Hemagglutinin monoclonal Antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Influenza A virus H3N2 Hemagglutinin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
HostMouse
Size20ul, 100ul
ClonityMonoclonal
PurificationProtein A/G
Formulation0.2 μm filtered solution in PBS
BackgroundThe influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
ImmunogenRecombinant H3N2 HA protein
Storage ConditionStore at -20℃. Avoid freeze / thaw cycles.
Shipping ConditionThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Cross-reactivityInfluenza A H3N2 (A/Babol/36/2005) Neuraminidase / NA
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
FAQ
  • Q1- 该抗体适用于哪些实验?

    适用于ELISA、免疫荧光(IF)、免疫组化(IHC)及中和实验,特异性检测H3N2亚型流感病毒的血凝素(HA)蛋白。

  • Q2- 为什么选择小鼠单克隆抗体?

    单克隆抗体具有高批次一致性和特异性,适合需要高重复性的实验(如诊断试剂开发)。

  • Q3- 能否识别其他流感亚型(如H1N1)的HA蛋白?

    不,该抗体针对H3N2 HA蛋白表位设计,需验证交叉反应性后再用于其他亚型。

  • Q4- 推荐的稀释比例是多少?

    稀释比例因实验而异,建议ELISA 1:1000,IF/IHC 1:200起,需预实验优化。

  • Q5- 如何保存抗体?

    长期保存需分装于-20℃,避免反复冻融;短期使用可4℃保存(含防腐剂)。

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