MA2606
Hsc70/HSPA8 antibody, Heat shock 70 kDa protein 8 antibody, heat shock 70kDa protein 8 antibody, HSC54 antibody, Hsc70 antibody, HSC71 antibody, HSP71 antibody, HSP73 antibody, HSPA10 antibody, HSPA8 antibody, LAP1 antibody, NIP71 antibody
| Alias | Hsc70/HSPA8 antibody, Heat shock 70 kDa protein 8 antibody, heat shock 70kDa protein 8 antibody, HSC54 antibody, Hsc70 antibody, HSC71 antibody, HSP71 antibody, HSP73 antibody, HSPA10 antibody, HSPA8 antibody, LAP1 antibody, NIP71 antibody |
| Catalog Number | MA2606 |
| Product Description | The Mouse Anti Human Hsc70/HSPA8 monoclonal Antibody was obtained by affinity purification from a mouse immunized with a purified human Hsc70 protein (P11142 70 kDa) |
| Host | Mouse |
| Size | 50ug, 100ug |
| Clonity | Monoclonal |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Formulation | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
| Background | HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061) |
| Immunogen | Human Hsc70 protein (P11142 70 kDa) |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Shipping Condition | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Stability | stable at -20 ° C |
| Cross-reactivity | Human, Mouse, Rat |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
是，Hsc70（HSPA8）在热休克或氧化应激时上调，适用于Western blot（1:1000）或免疫荧光（1:200）检测应激模型中的表达变化。
特异性结合HSPA8，交叉反应率＜0.1%（经HSP70/HSP90 KO细胞验证）。
细胞裂解液需含ATP（1 mM）以稳定Hsc70-底物复合物，避免反复冻融。
是，结合Protein G磁珠，用于富集Hsc70互作蛋白（如BAG3）。
液体4℃保存6个月，-20℃保存2年（含50%甘油）。
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