Guinea Pig Anti Human RBPMS Polyclonal Antibody
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产品编号
MA1605
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别名
RBPMS Guinea Pig Polyclonal Antibody, RBPMS Guinea Pig pAb
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规格
- 50ul
- 100ul
产品介绍
| Alias | RBPMS Guinea Pig Polyclonal Antibody, RBPMS Guinea Pig pAb |
| Catalog Number | MA1605 |
| Product Description | The Guinea Pig Anti Human RBPMS Polyclonal Antibody was obtained by affinity purification from a guinea pig immunized with purified synthetic peptide within human rbpms 1-30 conjugated to keyhole limpet haemocyanin.. |
| Host | Guinea Pig |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Concentration | 1 mg/ml |
| Purification | Immunogen affinity purified |
| Formulation | 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide. |
| Background | This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. |
| Immunogen | Synthetic peptide within human rbpms 1-30 conjugated to keyhole limpet haemocyanin. |
| Storage Condition | Store at 4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Shipping Condition | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Cross-reactivity | Mouse,Rat |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
FAQ
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Q1- RBPMS蛋白的功能是什么？
RBPMS参与RNA结合及转录后调控，在神经元和某些肿瘤细胞中高表达。
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Q2- 该抗体能否用于免疫组化（IHC）？
是的，已验证用于人组织切片的IHC，建议优化抗原修复条件。
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Q3- 是否识别小鼠或大鼠的RBPMS？
需比对物种间RBPMS序列同源性，可能需特定种属验证。
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Q4- 推荐阳性对照组织？
人视网膜或神经组织（如大脑皮层）可作为阳性对照。
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Q5- 抗体工作液如何配制？
建议起始稀释比例1:200（IHC）或1:1000（WB），根据信号强度调整。
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