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Streptococcus Pyogenes IdeS Protein, His Tag

Streptococcus Pyogenes IdeS Protein, His Tag

产品编号

KMP4414

别名

免疫球蛋白G降解酶蛋白, IdeS, IdeS Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias免疫球蛋白G降解酶蛋白, IdeS, IdeS Protein
Catalog NumberKMP4414
Product DescriptionThe Streptococcus Pyogenes IdeS Protein, His Tag(KMP4414) is produced in E. coli. A DNA sequence encoding the streptococcus pyogenes IdeS (F8V4V0-1) (Asp30-Asn341) was expressed with a polyhistidine tag at the N-terminus.
Molecular NameIdeS
SpeciesStreptococcus Pyogenes
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, 50% Glycerol, pH6.6
BackgroundIdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight36.2 kDa

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