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E. coli LON PROTEASE Protein, His Tag

E. coli LON PROTEASE Protein, His Tag

产品编号

KMP4411

别名

蛋白酶La, LON PROTEASE, LON PROTEASE Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias蛋白酶La, LON PROTEASE, LON PROTEASE Protein
Catalog NumberKMP4411
Product DescriptionThe E. coli LON PROTEASE Protein, His Tag(KMP4411) is produced in E. coli. A DNA sequence encoding E.coil Lon (P0A9M0) (Met1-Lys784) was expressed with a polyhistidine tag at the C-terminus.
Molecular NameLON PROTEASE
SpeciesE. coli
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, 10% Glycerol, pH7.4
BackgroundLon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, thereby protecting the cell from various extracellular stresses, including oxidative stress. The intellectual disability-associated and thalidomide-binding protein cereblon (CRBN) contains a large, highly conserved Lon domain. The Lon ATP-dependent protease plays an important role in regulating many biological processes in bacteria.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight88.3 kDa

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